Manifestaciones oftalmológicas de la infección por toxoplasma en paciente portador del virus de la inmunodeficiencia humana. Descripción de un caso / Ophthalmic manifestations of toxoplasmosis in a human immunodeficiency virus-positive patient. Description of a case

La toxoplasmosis es una infección de distribución mundial causada por Toxoplasma gondii, que infecta a una gran proporción de la población mundial. Solo bajo ciertas circunstancias de inmunosupresión grave, el parásito puede reactivarse y causar enfermedad. La forma más frecuente de presentarse la enfermedad en los pacientes portadores del virus de la inmunodeficiencia humana (VIH) es la de abscesos encefálicos. Dentro de las formas extracerebrales tenemos la coriorretinitis toxoplásmica, la que daría lugar a la forma de retinitis crónica activa de lenta evolución. El diagnóstico lo hace el oftalmólogo observando el fondo de ojo y se confirma por la cicatrización obtenida después del tratamiento específico. Se presenta un caso de un paciente diabético e infectado por el VIH, al que en la retinografía ambulatoria anual de control se le detecta una lesión cicatricial toxoplásmica. Se decidió una conducta terapéutica conservadora con controles periódicos para la detección de posible activación de la enfermedad (AU)

Toxoplasmosis is an infection of worldwide distribution caused by Toxoplasma gondii, and infects a large proportion of the world population. Only under certain circumstances of severe immunosuppression can the parasite reactivate and cause disease. The most common form of presentation of this pathology in patients with positive HIV is the brain abscess. One of the extra-cerebral forms is toxoplasmic chorioretinitis, which could lead to a chronic active form of a slowly progressive retinitis. Diagnosis is made by observing the eye fundus and confirmed by the scarring obtained after specific treatment. We report a case of a patient with diabetes and positive HIV, in whom a toxoplasmic scar injury was detected in the annual retinography follow-up. A conservative therapeutic approach was decided, with regular check-ups for possible detection of disease activation (AU)

[Ophthalmic manifestations of toxoplasmosis in a human immunodeficiency virus-positive patient. Description of a case]. / Manifestaciones oftalmológicas de la infección por toxoplasma en paciente portador del virus de la inmunodeficiencia humana. Descripción de un caso.

Toxoplasmosis is an infection of worldwide distribution caused by Toxoplasma gondii, and infects a large proportion of the world population. Only under certain circumstances of severe immunosuppression can the parasite reactivate and cause disease. The most common form of presentation of this pathology in patients with positive HIV is the brain abscess. One of the extra-cerebral forms is toxoplasmic chorioretinitis, which could lead to a chronic active form of a slowly progressive retinitis. Diagnosis is made by observing the eye fundus and confirmed by the scarring obtained after specific treatment. We report a case of a patient with diabetes and positive HIV, in whom a toxoplasmic scar injury was detected in the annual retinography follow-up. A conservative therapeutic approach was decided, with regular check-ups for possible detection of disease activation.

[Horseshoe kidney, stone disease and prostate cancer: a case presentation]. / Riñón en herradura, enfermedad litiásica y adenocarcinoma de próstata. Presentación de un caso clínico.

The horseshoe kidney is the most common congenital renal fusion anomalies. It occurs in 0.25% of the population, or 1 in every 400 people. It is more frequent in males (ratio 2:1). The most observed complication of horseshoe kidney is stone disease, although there may be others such as, abdominal pain, urinary infections, haematuria, hydronephrosis, trauma and tumours (most commonly associated with hypernephroma and Wilms tumour). We describe a case of a male patient with horseshoe kidney, stone disease and adenocarcinoma of the prostate. One carrier of this condition who suffered a transitional cell carcinoma of the prostate was found in a review of the literature.

[Mucosecretor adenocarcinoma of the lung with pleural involvement presenting as a pneumothorax. Presentation of a clinical case]. / Adenocarcinoma mucosecretor de pulmón con diseminación pleural que se manifiesta con neumotórax. Presentación de un caso clínico.

The combination of a pneumothorax and lung cancer is rare and diagnosis is complex. Clinical suspicion of cancer must be based on radiological findings and the existence of risk factors. We discuss the mechanisms involved in the development of pneumothorax in patients with lung cancer, as well as the clinical significance, the recommended diagnostic approach, and therapeutic guidelines.

[Stage IV stenosing sqamous cell carcinoma of the oesopahgus in a 41 year-old woman. A case presentation]. / Carcinoma epidermoide de esófago, estenosante, estadio IV, en mujer de 41 años. Descripción de un caso clínico.

OBJECTIVE: To present a clinical case of a 41 year-old woman, with a stage IV squamous cell carcinoma of the oesophagus. METHODS AND PATIENTS: We present a clinical case of 41 year-old woman with a history of type 2 diabetes mellitus, and resection of a haemosiderin plaque on the tongue. A space occupying lesion (SOL) was studied using ultrasound and Nuclear Magnetic Resonance (NMR), detecting, but unable to differentiate, a gradually increasing haemangioma or hepatocarcinoma. She was seen at the clinic due to dysphagia and loss of weight. In oesophagogastroscopy with biopsy a squamous cell carcinoma of the oesophagus was diagnosed. The Computed Tomography (CT) of the neck, thorax and abdomen showed a stenosing tumour in the oesophagus with metastasis in the lungs and left adrenal gland, and a SOL in the liver compatible with a neo-formative process. The erythrocyte sedimentation rate was 55 mm. She was referred to Surgery and Oncology, who performed a gastrostomy for enteral feeding and started treatment with palliative chemotherapy. CONCLUSIONS: Squamous cell carcinoma of the oesophagus is very frequent. The two most important risk factors are alcoholism and nicotine poisoning. The dysphagia is the most common symptom (96% of the patients). The prognosis is a poor, with high mortality. Surgery is the standard treatment when the tumour is located. Chemotherapy and radiotherapy are palliative treatments, but has not shown to be very effective.